Lindsey Young Goodman earned her PhD from UC Berkeley studying Structure Activity Relationships (SAR) of a human macromolecular complex essential to cancer, neurodegeneration, heart disease, among others: the Class III Phosphatidylinositol 3 Kinase Complex through biophysical methods and in vitro reconstitution using single particle cryo-EM, Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS), biochemical assays using reconstituted lipid vesicles.

Her work was published as first-author publications in PNAS (2016), and Molecular Cell (2019), and PNAS (2019), along with review articles in Annual Reviews of Biochemistry. 

Lindsey became fascinated with visualizing the autophagic process inside the cell directly using cutting-edge technology and moved to UC San Diego in order to visualize intact molecular networks at the high spatial resolution currently achievable. 

It became clear that this field need more tools for molecular identification and at UCSD developed a new labeling system, published in Nature Methods in 2026. 

She has been invited to present on this work at Atlos Labs, HHMI at Janelia, at a Biophysical Society Platform Session, the University of Pennsylvania, Keystone conference, among others.